International Journal of
Information and Education Technology

Editor-In-Chief: Prof. Jon-Chao Hong
Frequency: Monthly
ISSN: 2010-3689 (Online)
E-mali: editor@ijiet.org
Publisher: IACSIT Press
 

OPEN ACCESS
3.9
CiteScore

IJIET 2026 Vol.16(3): 695-707
doi: 10.18178/ijiet.2026.16.3.2542

Clinical Reasoning-Driven Progress Evaluation of Medical Students Using Large Language Models

Heitor S. Mattosinho1,* , Fernando Valente2 , Gabriel Leite1 , Ligia Maria Cayres Ribeiro2 , Marco A. de Carvalho Filho2 , André Santanchè1

  • 1Institute of Computing, University of Campinas, Brazil
  • 2University Medical Center Groningen, University of Groningen, Netherlands

* Corresponding author

  • Manuscript receivedAugust 14, 2025
  • revisedSeptember 8, 2025
  • acceptedNovember 6, 2025
  • publishedMarch 13, 2026

Abstract

Evaluating medical students’ written answers to questions on a given topic can provide information about their mental representations of a disease―i.e., illness script. However, limitations in methods for assessing how medical students develop clinical expertise hinder the advancement of educational practices. This study, therefore, proposes a technique that utilizes semantic annotations of the students’ answers to trace a map of their knowledge concerning the topic of a question. Since manual text annotation is time- and effort-intensive, this study developed an innovative, illness-script-driven strategy using large language models. It identifies relevant medical information in the texts, creates a profile for each answer, clusters them, and categorizes the clusters. Practical experiments with Brazilian students demonstrate that the technique automatically traces consistent profiles from the responses, quantifying how knowledge of disease diagnosis evolves throughout the medical course.

Keywords

  • illness script
  • medical education evaluation
  • large language model
  • clustering profiles
IJIET-V16N3-2542

How to Cite

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Heitor S. Mattosinho, Fernando Valente, Gabriel Leite, Ligia Maria Cayres Ribeiro, Marco A. de Carvalho Filho, and André Santanchè, "Clinical Reasoning-Driven Progress Evaluation of Medical Students Using Large Language Models," International Journal of Information and Education Technology, vol. 16, no. 3, pp. 695-707, 2026. https://doi.org/10.18178/ijiet.2026.16.3.2542

Copyright & License

Copyright © 2026 by the authors. This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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